Facial Surgery

Nanografting

Nanografting is an advanced regenerative treatment that improves skin quality from within using your own stem cells and growth factors, enhancing texture, elasticity and radiance at a cellular level.

Procedure Time

1 hour

Results Last

Long-lasting regenerative improvements

Hospital Stay

Day case

Recovery Time

1-2 weeks

Time Off Work

Usually 2-5 days

Anaesthesia

Local anaesthetic

Exercise

After 1-2 weeks

Price

Price Confirmed on Consultation

Procedure

What is Nanografting?

Nanografting is the latest evolution of autologous fat grafting. Unlike traditional fat transfer, which is designed to restore volume, Nanografting focuses almost entirely on improving skin quality. A very small amount of fat is harvested and processed to isolate its regenerative components – including stem cells and growth factors – which are then injected into carefully selected areas of the face. Performed by Dr Yannis Alexandrides, the treatment uses your own purified biological tissue to stimulate healthier skin, improve collagen production and restore luminosity naturally.

Expected Effects & Benefits

Improves fine lines, crepiness and skin texture
Encourages collagen production and cellular renewal
Enhances overall skin vitality and radiance

Your Journey

Your Nanografting Journey

Your journey begins with a comprehensive consultation with Dr Yannis Alexandrides. He will take time to understand your concerns, medical history and desired result, alongside a detailed assessment of your facial anatomy, skin quality, volume distribution and the areas you would like to rejuvenate.

This allows Dr Yannis Alexandrides to determine whether Nanografting is appropriate for you and create a personalised treatment plan designed to improve skin and tissue quality while maintaining natural facial balance and your individual identity.

Ahead of your procedure, you will have a comprehensive pre-operative assessment with our nursing team. This includes a review of your medical history, current medications, lifestyle and overall health, alongside any physical assessment or clinical tests required for your individual treatment plan.

Our team will explain what to expect before and after your procedure, answer any questions and ensure you are appropriately prepared for your treatment and recovery.

Good nutrition, hydration and healthy lifestyle habits can help prepare your body for treatment and support the healing process. You will receive personalised guidance on medications, exercise, smoking cessation where appropriate, and practical preparation before your procedure.

Every recommendation is tailored to your individual health, lifestyle and treatment plan to ensure your preparation is appropriate for you.

Preparing the skin forms an important part of our 360° approach to facial rejuvenation. Ahead of your procedure, our team may recommend a personalised skincare programme or selected treatments to optimise skin quality and complement your Nanografting treatment.

Where appropriate, this may include ElixirMD Light Therapy, 111SKIN skincare or Dr Yannis Alexandrides’ Dramatic Healing Serum, selected according to your individual skin and treatment plan.

Our care continues well beyond your procedure. Following Nanografting, our clinical team will monitor your healing through scheduled reviews, with particular attention to the treated areas, donor site and your developing result.

You will receive personalised guidance on skincare, activity and caring for the treated areas during recovery. Where appropriate, an IV drip or other post-procedure support may form part of your individual aftercare programme.

As your recovery progresses, Dr Yannis Alexandrides and our clinical team will review your skin quality, facial balance and developing result at scheduled follow-up appointments.

Where appropriate, your long-term plan may incorporate 111SKIN, UltraClear laser resurfacing, regenerative treatments or other selected non-surgical treatments to complement your Nanografting result and support ongoing skin quality.

Procedure

How does Nanografting work?

Nanografting works by harvesting a small amount of fat and processing it using specialised filtration and refinement techniques that isolate the regenerative components – stem cells and growth factors – while removing unnecessary oils, blood and unwanted tissue. This concentrated solution is then placed beneath the skin using extremely fine cannulas. As healing progresses, these biological components stimulate collagen production, improve blood supply and encourage healthier cellular activity, allowing the skin to regenerate naturally over the months that follow.

UNDERSTANDING SKIN REGENERATION:

As skin ages, it gradually loses collagen, elastin and regenerative capacity.
This results in thinning skin, crepiness, fine lines and a loss of radiance.
Volume replacement alone cannot correct these changes to skin quality.

WHY REGENERATION MATTERS:

Dermal fillers add volume and anti-wrinkle injections reduce muscle movement.
Nanografting instead supports healthier tissue by encouraging natural regeneration beneath the surface.

Because the treatment uses your own tissue, there is virtually no risk of allergic reaction or rejection.

Procedure

Surgical Techniques & Technology

Fine Lines & Texture

Stimulates collagen production to soften fine lines and improve overall skin texture.

Crepey & Thinning Skin

Encourages tissue repair in delicate, thinning areas such as around the eyes and mouth.

Dull Complexion

Enhances blood supply and cellular activity to restore radiance and vitality.

Acne & Superficial Scars

May improve the appearance of selected superficial scarring through tissue regeneration.

Combined with Fat Transfer

Often performed alongside Facial Fat Transfer to restore both volume and skin quality together.

Delicate Eye Area

Targets fragile, thinning skin around the eyes where volume-based treatments are less suitable.

CO2 Laser Combination

Often combined with CO2 Laser Skin Resurfacing to enhance both skin quality and texture together.

Your Journey

The 5-Step Process

Consultation

A comprehensive facial and skin assessment with Dr Yannis Alexandrides to understand your concerns and create a personalised Nanografting treatment plan.

1

Preparation

Pre-operative health assessment and personalised guidance on lifestyle, skincare and tissue preparation ahead of your procedure.

2

Surgery

Nanografting performed using your own carefully processed fat, with treatment tailored to the areas requiring rejuvenation and your individual facial anatomy.

3

Recovery

Post-procedure guidance and structured clinical aftercare as swelling and bruising subside and the treated areas begin to settle.

4

Long Term Care

Ongoing clinical review, personalised skincare and selected regenerative or non-surgical treatments where appropriate to support skin quality and complement your result.

5

Your Journey

Recovery Timeline

1-2 Months

Swelling and bruising gradually settle at both the donor site and treated facial areas.

2-3 Months

Early improvements in skin brightness and texture may begin to appear.

6-12 Months

Collagen production and tissue regeneration continue, with skin quality steadily improving.

12+ Months

The most significant changes become visible as regeneration continues over three to six months.

Your Journey

Post surgery activity guidelines

Shower

48 HOURS

Avoid unnecessary pressure on treated areas and keep the donor site dry unless advised otherwise.

Driving

3-5 DAYS

Resume only when comfortable, alert and no longer taking strong pain relief.

Work

2-5 DAYS

Timing depends on your role, swelling and confidence returning to work.

Exercise

1-2 WEEKS

Begin gently and increase only once cleared by your surgeon.

Suitability & Safety

Am I suitable for Nanografting?

Ideal Candidate Profile

Nanografting may be suitable for patients who have: – Fine lines that persist despite skincare – Thin or fragile skin – Crepey skin around the eyes or mouth – Dull or tired-looking skin – Mild acne scarring or sun-damaged skin – A desire for natural rejuvenation without synthetic fillers Suitability is confirmed during consultation, based on your individual anatomy, skin condition and goals.

Risks & Complications

As with any procedure involving fat harvesting and injection, risks may include bleeding, infection, bruising, swelling, altered sensation, contour irregularities, asymmetry and, rarely, more serious complications. These risks are discussed in detail during consultation, alongside the steps taken to reduce them through careful planning, technique and aftercare.

Your Surgeon

Dr Yannis Alexandrides

Dr Yannis Alexandrides is internationally recognised for his expertise in facial rejuvenation, reconstructive surgery and regenerative treatments. Rather than simply treating visible signs of ageing, he focuses on restoring healthier skin at a biological level, using meticulous processing techniques designed to preserve the regenerative potential of your own cells.

Pricing

Overview

Every patient and procedure at 111 Harley St. is unique, which is why surgical pricing is tailored to your individual case rather than based on a one-size-fits-all approach.

The cost of your procedure will depend on factors such as your anatomy, the complexity of surgery, the technique required and your personalised treatment plan.

Following your consultation and assessment, our team will provide a clear, individualised quotation based on the surgery recommended for you.

Finance Calculator

Loan Amount: £5,000

£5,000 £7,500 £10,000 £12,500 £15,000

Term: 12 months

12 months 24 months 36 months 48 months

First Payment

0 Monthly Payment

0 Interest Rate*

0

*Interest rates are subject to status and individual credit score.

Resources

Reviews

     
 
 
      Posted on Google  
   
   Ellie Hook 
 3 September 2026
 
 
  I came to the 111 Harley Street for UltraClear laser treatment with Claudia Brand. She was absolutely incredible, talking me through the process and made me feel very safe. She was also brilliant throughout the process. I cannot wait to see my result! Thank you Claudia!
  
 
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   Jenna Nicholls 
 2 September 2026
 
 
  Really lovely team - thank you Anna and Jamy for looking after me during treatment! Can’t wait for the results 🥰
  
 
     Posted on Trustindex  
   
   Edward Smith 
 31 August 2026
 
 
  Very Impressed With My Rhinoplasty I had been unhappy with the shape of my nose for years and finally decided to look into rhinoplasty. Choosing the right surgeon and clinic was extremely important to me, so I spent a lot of time researching before booking my consultation at 111 Harley St. The consultation was detailed and reassuring, and I appreciated the focus on achieving a result that suited my face rather than simply changing my nose. The whole process was handled professionally, from the initial consultation through to the follow-up appointments. My nose now looks much more balanced with the rest of my face, and the improvement is significant without looking artificial.
  
 
     Posted on Google  
   
   Louise F 
 28 August 2026
 
 
  I had my consultation with Anna and honestly couldn’t have been happier with the experience. She took the time to really listen to all of my concerns and went through everything with me in so much detail, including the different treatment options. I really appreciated how thorough and attentive she was, and the whole consultation felt very personal and tailored specifically to me rather than a one-size-fits-all approach. I felt really comfortable and well looked after. I’m really happy with the experience and will definitely be coming back for my treatment. Thank you so much, Anna!
  
 
     Posted on Google  
   
   Mily Barnett 
 27 August 2026
 
 
  Spoke to Anna about all my skin concerns over a consultation - she was super helpful, knowledgeable and can’t wait to start my journey with 111 Skin. Thank you Anna.
  
 
     Posted on Google  
   
   Mia Raggett 
 25 August 2026
 
 
  Had a lovely consultation with Anna, helped me so much with my questions and was very friendly. Thanks!
  
 
     Posted on Google  
   
   Yasmine Rabah 
 20 August 2026
 
 
  Just did the thermale treatment and the whole experience with the staff and the treatment and care has been superb. I highly recommend. Will let you know how it goes with the other treatments that I will do:)
  
 
     Posted on Google  
   
   Kat M 
 19 August 2026
 
 
  Fantastic facial with Jamy and consultation with Anna. Would 100% recommend!
  
 
     Posted on Trustindex  
   
   Rosie Walker 
 17 August 2026
 
 
  A Wonderful Experience I decided to explore a Y Facelift after becoming increasingly unhappy with the loss of definition around my lower face. I was initially quite nervous about having facial surgery, so having a detailed consultation was really important to me. Everything was explained clearly and I felt comfortable asking lots of questions. I’m so pleased with the outcome my face looks fresher and more defined, but it still looks completely like me.
  
 
     Posted on Google  
   
   Anna 
 10 August 2026
 
 
  Amazing experience with Claudia. I was really nervous but she put me at ease and explained the process to me. I would definitely recommend coming here for all aesthetic treatments!
  
 
     Posted on Google  
   
   Altay Ali 
 7 August 2026
 
 
  Claudia Is always amazing, and I would highly recommend her services.
  
 
     Posted on Google  
   
   Robert White 
 4 August 2026
 
 
  Claudia was amazing! Really friendly, polite and professional. Will 100% be coming back.
  
 
     Posted on Trustindex  
   
   Jessica Thomas 
 4 August 2026
 
 
  The Best Decision I Made I had a facelift at 111 Harley Street. From my very first consultation, I felt completely comfortable and confident that I was in safe hands. The surgeon took the time to understand what I wanted to achieve and explained every stage of the process clearly, from the operation itself to the recovery and expected results. The care I received was outstanding from start to finish. Every member of the team was kind, professional, and incredibly supportive. They were always available to answer any questions, and I felt genuinely looked after throughout my entire journey. Now that I've fully recovered, I am absolutely delighted with the results. I look refreshed, younger, and far more confident, while still looking completely natural. The best compliment I've received is that people keep telling me I look really well without realising I've had surgery. It's exactly the subtle, natural result I was hoping for. Choosing 111 Harley Street was one of the best decisions I've made. The expertise, attention to detail, and exceptional aftercare exceeded all of my expectations. I would wholeheartedly recommend them to anyone considering a facelift.
  
 
     Posted on Google  
   
   Hannah Lucy 
 31 July 2026
 
 
  I had a consultation with Anna who was so knowledgeable and extremely friendly. The team were welcoming and I look forward to starting treatment.
  
 
     Posted on Google  
   
   Aashika Balaji 
 31 July 2026
 
 
  Claudia is excellent and incredibly intuitive
  
 
     Posted on Google  
   
   William Julian Taranu-Lee 
 29 July 2026
 
 
  Had such a lovely consultation at 111 Harley St. I felt so welcomed and comfortable in their hands, and really appreciated their honest cosmetic advice. Would absolutely recommend having a consultation at 111 Harley St. You won’t regret it :)
  
 
     Posted on Google  
   
   Bilgi P 
 28 July 2026
 
 
  +0
I had plastic surgery from doctor Ashvani in 2019 and he messed up my tummy completely. I lost all my sensation in my tummy area and after 7 years, I still regret of having tummy tuck with him. He stitched my whole tummy tuck area without leaving drainage after the operation. I ended up having this massive hole in my tummy area. I have the most horrible scars and I don’t wear bikini for not showing my belly button. You can see how bad his stitches are from the photo. Please do your research before you trust him so you don’t regret like I did. My friend had similar operation in Turkey and you would not even notice she had plastic surgery.my advice is  go to Turkey to have proper plastic surgery with surgeons who knows how do operate.
  
 
     Posted on Google  
   
   Georgia Westley 
 28 July 2026
 
 
  Had a consultation with Anna who helped with my skin concerns, she helped advice on treatments and products to support on my hyper pigmentation and dryness. Would highly recommend
  
 
     Posted on Google  
   
   Chloe L 
 27 July 2026
 
 
  Really pleased with my consultation with Anna. She explained everything clearly, and the skin scanning was very insightful. Everyone was warm and friendly – I’d highly recommend.
  
 
     Posted on Google  
   
   Zara Walsh 
 27 July 2026
 
 
  Thank you so much, great experience!
  
 
 
  
 
 
   Trustindex rating score: 4.9 of 5, based on 856 reviews,showing our latest reviews

Resources

Frequently Asked Questions

How is Nanografting different from Facial Fat Transfer?

Although both procedures use your own fat tissue, they have different objectives. Facial Fat Transfer restores volume, while Nanografting focuses on skin regeneration. The fat is processed differently to isolate regenerative cells and growth factors rather than preserving fat for structural volume replacement.

Is Nanografting painful?

The procedure is performed under local anaesthetic, so treatment itself is comfortable. Afterwards, most patients experience only mild tenderness at the donor site and temporary swelling in the treated areas, both of which usually resolve within a few days.

When will I see results?

Some improvements may become noticeable within the first few weeks, but the most significant changes develop gradually as collagen production increases, typically continuing over the following three to six months.

Can Nanografting be combined with other treatments?

Yes. Nanografting is frequently combined with procedures such as Facial Fat Transfer, Deep Plane Facelift, Blepharoplasty and CO2 Laser Skin Resurfacing to deliver comprehensive facial rejuvenation.

How long do the results last?

While the natural ageing process continues, the regenerative improvements achieved through Nanografting are long-lasting. Maintaining healthy skin through appropriate skincare, sun protection and a healthy lifestyle will help preserve your results.

Is Nanografting suitable for everyone?

Nanografting is suitable for many patients concerned with declining skin quality, although suitability depends on your individual anatomy, skin condition and aesthetic goals. Dr Yannis Alexandrides will recommend the most effective approach during consultation.