As we enter 2026, Plastic & Reconstructive Surgeon Dr Yannis Alexandrides reflects on another year in aesthetics, wellness and, of course, plastic surgery and what he expects to see more of in the new year.
His 2026 predictions include treatments already offered at his world-renowned clinic at 111 Harley St., along with ground-breaking technologies and buzzwords, such as Exosomes, that we heard so much about in 2025.
Laser treatments have been popular for years in various forms, and 111 Harley St. has led the way, keeping lasers a staple in its treatment menu. The latest addition is cold fibre laser, UltraClear, dubbed ‘the future of skin remodelling’, which tackles a range of skin concerns and can be used both with surgery and as a standalone, non-surgical treatment.
This advanced laser uses laser-coring techniques to resurface, remodel, and renew skin, and it is the first and only cold, ablative, fractional MIDIR 2910 nm Fibre Laser using 3DIntelliPulse technology. Results are truly transformative and come with minimal downtime compared to other resurfacing options available. The cold fibre laser precisely vaporises dull, damaged surface skin cells while treating deeper dermal layers with controlled thermal energy.
This process boosts collagen, elastin, and hyaluronic acid production for firmer, clearer, smoother skin with a significantly shorter recovery period. Dr Yannis predicts the technology will gain significant popularity throughout 2026 because it delivers exceptional results without compromising patient safety.
Long known for taking the least invasive approach and for a dedication to long-lasting results, Dr Yannis is confident that the shift toward regenerative treatments that improve skin quality will continue into the new year. Strengthening the skin and improving its quality can delay concerns such as lines, wrinkles, and crepiness that occur with age.
A buzzword throughout 2025, exosomes continue to gain popularity alongside other regenerative treatments such as polynucleotides to regenerate collagen and elastin, and as an alternative to dermal filler. Dr Yannis was so impressed with the results achieved for patients at his clinic, 111 Harley St., that he was inspired to develop the 111SKIN Exosomes Face Lift, an exceptional product duo designed to be used at home over the course of 4 weeks – and the perfect homecare to complement in-clinic treatments such as those offered. The products have a unique microspicule delivery system that delivers active ingredients twice as deep into the skin* for a more effective application.
In addition to regenerative treatments, as a Plastic Surgeon, Dr Yannis offers advanced procedures such as Nanografting, using the patient’s own growth factors and stem cells to strengthen the skin with stunningly natural results that stand the test of time. As the aesthetic landscape evolves, his clinic, 111 Harley St., continues to offer the services of a Consultant Nutritionist alongside their advanced procedures, with Dr Yannis believing firmly in the role the correct nutritional intake plays in the longevity of the skin.
*Measuring the penetration of Lactosome 55 at 0h and 1h after application of the Exosome Shot Serum with and without Microspicules
Not new for 2026, but undoubtedly more important than ever, bespoke treatment plans are something Dr Yannis confirms we will see into January and beyond. The standard treatment menu and a ‘one size fits all’ approach is now extremely dated and irrelevant in 2026.
Under Dr Yannis’ guidance, leading clinic 111 Harley St. has offered a 360-degree approach to aesthetics and plastic surgery for almost 25 years. Dr Yannis says, ‘ A combination of factors and techniques helps achieve the best outcome. Creating an immediately visible result is something many treatments can do, but results can be short-lived and knowing the right combination of treatments and products to generate a long-term effect that improves over time is an art that only comes with experience’.
He and his clinic team work closely with patients from consultation through their time under the clinic’s care. They carefully consider all options, allowing them to curate unique plans for each patient who visits the long-established address. Services include the latest advancements in aesthetic technologies, injectables, and surgical procedures, plus nutritionist services, Vitamin IV Drips, and science-backed 111SKIN products inspired by the clinic’s patients.
Dr Yannis is best known for his Deep Plane Facelift results and the Y Facelift technique he personally pioneered. Recently back from Brazil, where he lectured on the Deep Plane technique, sharing his secrets with surgeons from around the world, plus performed live surgeries showcasing his expertise. Dr Yannis has earned numerous accolades and is known globally for the results he achieves. He predicts techniques will keep evolving, and more surgeons will adopt the multifaceted approach he favours.
The Deep Plane technique is already incredibly advanced, and a far cry from the early face-lifting techniques from years ago, thanks to the way it lifts the layers of the face as a whole, repositioning them and
achieving incredibly natural outcomes for patients. Dr Yannis takes the technique to the next level, building treatments such as LED therapy, Endermologie, and ablative resurfacing lasers into his patient plans to encourage deep skin renewal.
In addition to the consultation, which is a highly important part of the process, he says, ‘The best outcomes involve a multifaceted approach. Prepping the skin and body ahead of time for recovery and healing processes is important. The surgery itself must be performed with precision and the correct technique. Then comes recovery. I like to use different technologies to accelerate the healing process and diminish the signs of scarring, along with treating concerns such as pigmentation that surgery alone cannot address’.
Dr Yannis has long favoured Micrografting and incorporated it into his facial procedures. He now predicts rising demand for Nanografting, a technique he uses with great success on patients at 111 Harley St.
Micrografting uses the body’s own fat cells to replenish areas that have lost volume from ageing or weight loss, while Nanografting can future-proof the skin with biological improvements. The process is similar for both Micrografting and Nanografting; both use the patient’s own biocompatible fat, but the latter breaks the fat down further before reinjecting stem cells and growth factors into the target area for natural results that improve skin quality.
Dr Yannis’ 360-degree approach has always included non-surgical treatments to support recovery, create a more comfortable patient experience, improve healing, and elevate overall outcomes. He predicts 2026 will see further advancements in plastic surgery practices.
He has personally already introduced the Elixir MD as the latest addition to his pre- and post-surgery protocols. Now incorporated into patient plans, the device uses advanced photobiomodulation technology to infuse energy into the skin with varying light wavelengths for seamless, swift surgical healing.
The technology forms part of 111 Harley St.’s commitment to superior patient outcomes, which begins ahead of their procedure with pre-op protocols that utilise blue light to reduce bacterial load, such as oils, toxins and secretions, to fortify skin ahead of surgery; and post-op protocols suited to all skin types 1-6 on the Fitzpatrick scale.
Alongside Endermologie treatments, Vitamin IV Drips, and other non-surgical treatments, Elixir MD is part of the clinic’s pre- and post-surgery protocols to ensure superior results for patients after plastic surgery.
All consultations are subject to the applicable charge at the time of booking. This is deducted from the cost of your procedure or treatment*
Surgical Procedures Virtual Consultation Fee
Dr Yannis: £200
Non-Surgical In-Clinic and Virtual Deposit
£50, which is redeemable against your treatment or refunded after your consultation if you decide not to proceed with your treatment plan.
